I began my career with a PhD on early development of the brushtail possum at La Trobe University (Vic), with a view to identifying immunocontraceptive targets for possum biocontrol in New Zealand. After subsequent post-doctoral positions (Cambridge University, UK; University of Auvergne, France; Sloan-Kettering Institute, NY; University of Melbourne, Australia) focussed on early mouse development and marsupial reproduction and development, I have now returned full circle to the problem of invasive vertebrate pests. However, the general theme of the research in my lab more broadly encompasses genome editing with ecologically therapeutic applications, including gene drives for vertebrate pest control, engineering cane toad toxin resistance in the threatened northern quoll, engineering resistance to chytridiomycosis in amphibians, and thylacine de-extinction (with Prof. Andrew Pask).